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生理信號測量

神經遞質檢測係統

時間_|永盛彩票网是真的吗:2016-09-27來源|-云顶娱乐场官方:本站作者|-玫琳凯之窗 登入:玉研儀器

詳細介紹

神經遞質實時檢測係統應用快速掃描循環伏安法(FSCV)技術___长城i7,快速實時監測動物體內的兒茶酚胺類神經化學物質的含量(如多巴胺|-_pk 3调试,去甲腎上腺素__淘金币换购,血清素等)_-_易彩彩票可靠吗。係統使用了碳纖維生物傳感器-_智行彩票首页,可在大小鼠身體上實現短期的快速測量_|注册送彩票彩金。


係統有兩種款式___宫锁珠帘定妆照:一種為用於大鼠的無線遙測係統-__108娱乐app新3d是什么,一種為應用到小鼠的有線遙測係統_||135彩票官方。


技術優勢:
√ 良好的空間分辨率-直徑34um 碳纖維
√ 良好的時間分辨率- 5-10 sweeps/s
 準確度-使用現有的可定義的明確兒茶酚胺類標記物1号计划彩票软件在哪里下载,排除了其他種類物質的幹擾|-|若禾。
√ 采樣速率: 5k/s (大鼠係統)_-|运盛娱乐app图片,或者10K/s(小鼠係統)

工作原理-_-可怜九月初三夜全诗:
生物胺類物質的含量通過快速循環性的施加電壓到一根植入式碳纖維傳感器-_-移动电源加工,然後檢測相應的產生的電流變化進行測定__-22选5开奖结果今天。係統使得在進行詳細的行為學研究的同時-__skinselect,可以測量自發產生的亞秒級的神經遞質釋放事件_-|与狼共舞oa。無論是有線還是無線係統|||晚托网,都可以在可選的量程(-0.6-+1.5V)範圍內_-|2019年白小姐全年资料,進行250-400V/s的掃描檢測--|解放军466医院耳鼻喉。所有係統同時還內置支持外部刺激的控製|_亿贝平台简介。


軟件:

係統配套軟件不僅支持傳統的短期測量模式(記錄2分鍾以內的數據)|--阿ben 张本渝,同時還支持擴展的連續長期記錄模式_-美国乒乓球队。除此之外_|_2019最火现金棋牌官网,本軟件的特點還包括背景噪音消除|现任国家领导人排名,熱點圖|__139期香港内部传真,3D可視化視圖|-中大恒基官网,可選的濾波以及動態的伏案圖__-上海蹦极。數據可以導出為通用的EXCEL格式文件-__关予涵。另外--_雨小薇,軟件還支持整合同步視頻捕捉|--至尊六舍彩论坛,以便適合於動物行為與生物物質釋放關係的同步研究_-|轩辕传奇破幽谷怎么打。


FAST SCAN CYCLIC VOLTAMMETRY SYSTEM

Pinnacle’s FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM is specifically designed to simplify the measurement of catecholamines (i.e., dopamine, norepinephrine, and serotonin). Pinnacle offers turn-key systems for both mice and rats. Both the wireless rat system and the tethered mouse system use carbon fiber sensors to enable short-term measurement in the brains of freely moving animals.





HOW IT WORKS

Biogenic amine levels are detected by rapidly cycling a voltage across an implanted carbon fiber sensor and measuring the resultant current. Our systems can measure spontaneous sub-second neurotransmitter release events while conducting detailed behavioral studies. Both the wireless and tethered systems sweep from 250 to 400 V/s in a user-selectable range spanning -1.1 to +1.3 V. All systems have built-in support for controlling an external stimulus.

l  Voltage Span: -1.1 V to +1.3 V

l  Range: 250 – 400 V/s 

l Sweeps/second: 5 - 10 

l Points/sweep: 1000 



Analysis

Dopamine (blue), serotonin (green), and norepinephrine (pink) have specific voltammogram profiles when detected by FSCV.


The TETHERED FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM allows researchers to harness the powerful genetics of the mouse model to address underlying mechanisms of biogenic neurotransmitter release and function. A headmounted FSCV board sends signals through a low-torque commutator to an interface box that streams data to the host PC. The system comes with Pinnacle’s FREE 8500 software.



1. The FSCV interface box provides access to stimulus lines and transmits data to PAL-8500 software.

2. A low-torque commutator, which is mounted above the cage, allows for unencumbered freedom of movement.

3. Signals are amplified and filtered at the head of the animal using our headstage, which ensures the delivery of clean, artifact-free data.

4. Stereotaxically placed guide cannulas allow easy insertion of carbon fiber sensors. Headmounts are affixed to the skull with dental acrylic and act as a connection port for the headstage.

 




CARBON FIBER


Pinnacle’s FSCV system uses CARBON FIBER SENSORS (CFSs) to measure the presence of dopamine and other catecholamines in the brains of freely moving animals. Our sensor is a 34 µm diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica. All Pinnacle CFSs require an Ag/AgCl reference electrode.


Our sensor is a 34 um diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica.

 




CARBON FIBER SENSORS

Carbon fiber sensors are ordered by cannula type and whether the researcher needs to remove them from the cannula for post-calibration. CFS-F sensors are fixed in the cannula and cannot be removed for post-calibration_365彩票买不了吗。



FSCV PAL-8500 SOFTWARE PACKAGE

The FSCV system includes Pinnacle’s FREE PAL-8500 software, which supports traditional, short recording paradigms (recordings of two minutes or less) as well as longer-term recordings that use an extended continuous mode. Furthermore, the suite supports integrated, synchronized video recording, which allows monitoring of animal behavior simultaneously with biogenic amine release.

 


Additional features of this software include:
• Background Subtraction
• 3D Visualization 
• User-Selectable Filters 
• Heat Maps 
• Animated Voltammograms
• Export to Third-Party Packages 




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