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地址_-1950彩票娱乐平台:上海市閔行區興梅路485號 XingMei Rd 485,Shanghai,China

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生理信號測量

神經遞質檢測係統

時間|_注册了趣头条安全么:2016-09-27來源|__易彩易彩福地app:本站作者-_众盈彩票能赚钱吗:玉研儀器

詳細介紹

神經遞質實時檢測係統應用快速掃描循環伏安法(FSCV)技術---01彩票是正规的吗?,快速實時監測動物體內的兒茶酚胺類神經化學物質的含量(如多巴胺_无主之地2发型不好的日子,去甲腎上腺素_||易富彩票平台,血清素等)_|-智投彩票。係統使用了碳纖維生物傳感器-_22选5河南最新开奖公告,可在大小鼠身體上實現短期的快速測量_-158彩票人工计划。


係統有兩種款式||汗癣图片:一種為用於大鼠的無線遙測係統||丝丝发图片,一種為應用到小鼠的有線遙測係統-台湾桔熊。


技術優勢:
√ 良好的空間分辨率-直徑34um 碳纖維
√ 良好的時間分辨率- 5-10 sweeps/s
 準確度-使用現有的可定義的明確兒茶酚胺類標記物-__淘宝试用什么意思,排除了其他種類物質的幹擾|-北仑教科网。
√ 采樣速率: 5k/s (大鼠係統)|_|118彩票网是正规大平台吗,或者10K/s(小鼠係統)

工作原理_|_2019手机彩票app:
生物胺類物質的含量通過快速循環性的施加電壓到一根植入式碳纖維傳感器_|易彩票234老版本下载,然後檢測相應的產生的電流變化進行測定360彩票官网走势。係統使得在進行詳細的行為學研究的同時说句悄悄话,可以測量自發產生的亞秒級的神經遞質釋放事件|-灵异森林女尸图片。無論是有線還是無線係統_||蝗虫多少钱一斤,都可以在可選的量程(-0.6-+1.5V)範圍內-_中央1台在线直播观看,進行250-400V/s的掃描檢測|--c7000。所有係統同時還內置支持外部刺激的控製|停车场尺寸。


軟件:

係統配套軟件不僅支持傳統的短期測量模式(記錄2分鍾以內的數據)||-众赢彩APP,同時還支持擴展的連續長期記錄模式|-陈奎元简历。除此之外-_-榆林市人力资源和社会保障网,本軟件的特點還包括背景噪音消除-_|花样少女是多大,熱點圖-_dnf战争英雄之无双太刀,3D可視化視圖_-_青岛台东洗头房,可選的濾波以及動態的伏案圖--_娱乐天地点检安卓版。數據可以導出為通用的EXCEL格式文件-_-莱州教育科研网。另外--_我要的是无话不说,軟件還支持整合同步視頻捕捉||_许小年微博,以便適合於動物行為與生物物質釋放關係的同步研究_-人族大讲堂。


FAST SCAN CYCLIC VOLTAMMETRY SYSTEM

Pinnacle’s FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM is specifically designed to simplify the measurement of catecholamines (i.e., dopamine, norepinephrine, and serotonin). Pinnacle offers turn-key systems for both mice and rats. Both the wireless rat system and the tethered mouse system use carbon fiber sensors to enable short-term measurement in the brains of freely moving animals.





HOW IT WORKS

Biogenic amine levels are detected by rapidly cycling a voltage across an implanted carbon fiber sensor and measuring the resultant current. Our systems can measure spontaneous sub-second neurotransmitter release events while conducting detailed behavioral studies. Both the wireless and tethered systems sweep from 250 to 400 V/s in a user-selectable range spanning -1.1 to +1.3 V. All systems have built-in support for controlling an external stimulus.

l  Voltage Span: -1.1 V to +1.3 V

l  Range: 250 – 400 V/s 

l Sweeps/second: 5 - 10 

l Points/sweep: 1000 



Analysis

Dopamine (blue), serotonin (green), and norepinephrine (pink) have specific voltammogram profiles when detected by FSCV.


The TETHERED FAST SCAN CYCLIC VOLTAMMETRY (FSCV) SYSTEM allows researchers to harness the powerful genetics of the mouse model to address underlying mechanisms of biogenic neurotransmitter release and function. A headmounted FSCV board sends signals through a low-torque commutator to an interface box that streams data to the host PC. The system comes with Pinnacle’s FREE 8500 software.



1. The FSCV interface box provides access to stimulus lines and transmits data to PAL-8500 software.

2. A low-torque commutator, which is mounted above the cage, allows for unencumbered freedom of movement.

3. Signals are amplified and filtered at the head of the animal using our headstage, which ensures the delivery of clean, artifact-free data.

4. Stereotaxically placed guide cannulas allow easy insertion of carbon fiber sensors. Headmounts are affixed to the skull with dental acrylic and act as a connection port for the headstage.

 




CARBON FIBER


Pinnacle’s FSCV system uses CARBON FIBER SENSORS (CFSs) to measure the presence of dopamine and other catecholamines in the brains of freely moving animals. Our sensor is a 34 µm diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica. All Pinnacle CFSs require an Ag/AgCl reference electrode.


Our sensor is a 34 um diameter carbon fiber housed in a silica sheath that extends 0.5 mm beyond the end of the silica.

 




CARBON FIBER SENSORS

Carbon fiber sensors are ordered by cannula type and whether the researcher needs to remove them from the cannula for post-calibration. CFS-F sensors are fixed in the cannula and cannot be removed for post-calibration-_|完颜璟。



FSCV PAL-8500 SOFTWARE PACKAGE

The FSCV system includes Pinnacle’s FREE PAL-8500 software, which supports traditional, short recording paradigms (recordings of two minutes or less) as well as longer-term recordings that use an extended continuous mode. Furthermore, the suite supports integrated, synchronized video recording, which allows monitoring of animal behavior simultaneously with biogenic amine release.

 


Additional features of this software include:
• Background Subtraction
• 3D Visualization 
• User-Selectable Filters 
• Heat Maps 
• Animated Voltammograms
• Export to Third-Party Packages 




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